Protective Role of Royal Jelly against Histological Effects of Aluminum Chloride on Testes of Male Rats

The aim of this study is to investigate the protective role of the royal jelly on the histological alterations of testes induced by aluminum chloride (AlCl3). The first group of the rats was negative control group. The four treatment groups were received 20 mg AlCl3 /kg body weight, one of them was considered the positive control group, The three other groups were received the same dose of AlCl3 and subdivided according to the different concentration of the concentrations of royal jelly (50, 100 and 200 mg/kg). All treated doses were given orally by gastric intubation and the experiment was continued daily for 60 days. Due to experimental intoxication with AlCl3, the microscopic examination for the testes in rats revealed numerous histological lesions in the seminiferous tubules and the interstitial tissue. In contrast, the histopathologic changes of testes were partially reversed by treatment with royal jelly and the testes appeared with nearly normal structure. It may be concluded that royal jelly revealed protective effect against the reproductive toxicity of AlCl3