Pre-natal maternal stress and its potential correlation to attention deficit hyperactivity disorder (ADHD): An exploration into the potential correlation between the prevalence of chronic stress among a sample of Eastern Cape (South African) women during pregnancy and the diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) in their children by the time they are of school-going age

This study is an exploration into the potential correlation between the prevalence of chronic stress during pregnancy among a sample of Eastern Cape (South African) mothers and a diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) in their school-going children. The theoretical framework on which this study is based is Barker’s Developmental Origins of Health and Disease (DOHaD) model. This model proposes that in utero development is influenced by the intrauterine milieu provided by the mother, where even a slight deviation to this environment during critical periods of development can lead to alterations in structure, physiology and metabolism in the child via fetal programming, which, depending on the cause, timing, duration and intensity of the stress, can cause pervasive, long-lasting consequences to disease and health later in life. This particular study examines existing literature regarding the phenomenon of how prenatal maternal stress (PNMS), as the adverse in utero influence, exerts a long-lasting negative effect on fetal development in the form of ADHD in childhood, and compares these findings to the circumstances surrounding a sample of 60 mothers whose school-going children have been diagnosed with ADHD. A mixed methods approach was used in this study, incorporating firstly a quantitative strand of Eastern Cape mothers where the prevalence and range of chronic stress during gestation was explored. From this sample, a qualitative sample was selected to provide more in-depth information regarding their stressful pregnancies. The flipside of the DOHaD model is that because of fetal developmental plasticity, positive in utero influences can undo the harmful effects caused by over-exposure to stress hormones, thereby enhancing fetal development. Unfortunately, this study highlighted how few mothers were aware of the positive influence a relaxation intervention programme could have on reducing stress which could alter the trajectory of their child’s development. The significant role that a genetic predisposition towards ADHD plays is not being debated. However, this study has provided much needed insight about PNMS as a negative influence on gestational development that could lead to the onset of, or exacerbation of ADHD traits