Influence of candidate genes FASN and SCD1 on milk fatty acid composition

Masnokiselinski sastav mlijeka uvjetovan je nizom čimbenika među kojima genski markeri imaju sve veći značaj. Istraživanja na području pronalaženja genskih markera potencijalnih kandidatnih gena te njihovog utjecaja na količinu i sastav mlijeka pružaju mogućnost njihove primjene u selekciji mliječnih krava na visoku mliječnost i željeni sastav mlijeka. U ovom radu dati ćemo osvrt na dosadašnja istraživanja dva kandidatna gena: sintazu masnih kiselina (FASN, engl. fatty acid synthase) i stearoil-CoA desaturaza 1 (SCD1, engl. stearoyl-CoA desaturase1), koji su odgovorni za sintezu masnih kiselina te imaju znatan utjecaj na masnokiselinski sastav mlijeka.Milk fatty acid composition is influenced by a number of factors, including genetic markers which are of increasing importance today. Research in the field of genetic markers, with the discovery of potential candidate genes and their impact on the quantity and composition of milk, offers the possibility of its application in the selection of dairy cows for high milk yield and desired milk composition. In this paper, we present an overview of previous studies of two candidate genes, fatty acid synthase (FASN) and stearoyl- CoA desaturase 1 (SCD1), which are responsible for fatty acid synthesis, and thus affect the milk fatty acid composition