Design and testing of an integrated circuit for multi-electrode neural recording

Journal ArticleWe have developed a single-chip neural recording system with wireless power delivery and telemetry. The 0.5-μm CMOS IC is designed to be bonded to the back of a 100-channel Utah Electrode Array. A pad near each amplifier allows connection of the chip to the MEMS electrode array. The complete Integrated Neural Interface will receive power wirelessly through a 2.64-MHz inductive link. A clock, regulated supply, and commands are derived from the power signal .The neural amplifiers each have a gain of 60 dB. A 10-bit charge-redistribution ADC is used to digitize the signal from one amplifier selected with an analog MUX. Digitizing all channels simultaneously would generate prohibitively high data rates; therefore, we perform data reduction by incorporating one-bit "spike detectors" into each amplifier. Neural data is transmitted off chip using an -integrated 433-MHz FSK transmitter. The chip measures 4.7×5.9 mm2 and consumes 13.5 mW of power