Add to ORKGJournal ArticleThe 5' ends of many bacterial transcripts are important in determining mRNA stability. A series of Shine-Dalgarno (SD) sequence changes showed that the complementarity of the SD sequence to the anti-SD sequence of 16S rRNA correlates with lacZ mRNA stability in Escherichia coli. Several initiation codon changes showed that an efficient initiation codon is not necessary to maintain lacZ mRNA stability. A stop codon in the 10th codon of lacZ increased mRNA stability. Therefore, ribosomal binding via the SD sequence but not translation of the coding region is necessary to maintain lacZ mRNA stability
Silencing of the lacZ gene in Escherichia coli was attempted by means of the expression of antisense...
SummaryThe rate of protein synthesis varies according to the mRNA sequence in ways that affect gene ...
Analysis of the Escherichia coli transcriptome identified a unique subset of messenger RNAs (mRNAs) ...
dissertationA series of initiation codon and Shine-Dalgarno (SD) sequence changes shows that the SD ...
We have shown previously that when the Escherichia coli chromosomal lacZ gene is put under the contr...
The Escherichia coli lacZ gene was used as a model system to identify specific sequence elements aff...
Journal ArticleBase pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the...
Efficient and accurate protein synthesis is crucial for organismal survival in competitive environme...
Bacterial translation comprising of three steps: initiation, elongation and termination is a highly ...
Translation is a crucial factor in determining the rate of protein biosynthesis; for this reason, ba...
Like bacterial genes, most plastid (chloroplast) genes are arranged in operons and transcribed as po...
Protein synthesis by ribosomes takes place on a linear substrate but at non-uniform speeds. Transien...
Sixty-one codons specify 20 amino acids, offering cells many options for encoding a polypeptide sequ...
The acquisition of protein secondary and tertiary structure depends on the primary sequence of amino...
We have constructed synthetic coding sequences for the expression of poly(α,l-glutamic acid) (PLGA) ...
Silencing of the lacZ gene in Escherichia coli was attempted by means of the expression of antisense...
SummaryThe rate of protein synthesis varies according to the mRNA sequence in ways that affect gene ...
Analysis of the Escherichia coli transcriptome identified a unique subset of messenger RNAs (mRNAs) ...
dissertationA series of initiation codon and Shine-Dalgarno (SD) sequence changes shows that the SD ...
We have shown previously that when the Escherichia coli chromosomal lacZ gene is put under the contr...
The Escherichia coli lacZ gene was used as a model system to identify specific sequence elements aff...
Journal ArticleBase pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the...
Efficient and accurate protein synthesis is crucial for organismal survival in competitive environme...
Bacterial translation comprising of three steps: initiation, elongation and termination is a highly ...
Translation is a crucial factor in determining the rate of protein biosynthesis; for this reason, ba...
Like bacterial genes, most plastid (chloroplast) genes are arranged in operons and transcribed as po...
Protein synthesis by ribosomes takes place on a linear substrate but at non-uniform speeds. Transien...
Sixty-one codons specify 20 amino acids, offering cells many options for encoding a polypeptide sequ...
The acquisition of protein secondary and tertiary structure depends on the primary sequence of amino...
We have constructed synthetic coding sequences for the expression of poly(α,l-glutamic acid) (PLGA) ...
Silencing of the lacZ gene in Escherichia coli was attempted by means of the expression of antisense...
SummaryThe rate of protein synthesis varies according to the mRNA sequence in ways that affect gene ...
Analysis of the Escherichia coli transcriptome identified a unique subset of messenger RNAs (mRNAs) ...