dissertationThree hour incubations of isolated fat cells from rat epididymal fat pads with 8xlO~°M dexamethasone causes a significant increase in the sphingomyelin content of fat cell ghosts prepared from these cells. Other phospholipids, methylated fatty acids from the phospholipids and cholesterol do not change significantly. It is postulated that the dexamethasone effect to increase sphingomyelin in fat cell membranes may be related to the mechanism by which glucocorticoids cause a decrease in glucose uptake by fat cells
Recent studies have demonstrated that fatty acids in-duce insulin resistance in skeletal muscle by b...
Peripheral insulin resistance (IR) is one of the main side effects caused by glucocorticoid (GC)-bas...
There are few and contradictory data on the role of excessive accumulation of intracellular sphingol...
Hypercortisolemia and glucocorticoid treatment cause elevated level of circulating free fatty acids ...
GLUT2 expression is strongly decreased in glucose-unresponsive pancreatic beta cells of diabetic rod...
Type 2 diabetes mellitus (T2DM) is a complex disease involving various physiological factors, hormon...
Glucocorticoid hormones constitute an integral component of the response to stress, and many of the ...
Polycystic ovary syndrome (PCOS) is a reproductive and metabolic disorder characterized by hyper...
Patients with glucocorticoid (GC) excess, Cushing's syndrome, develop a classic phenotype characteri...
Patients with glucocorticoid (GC) excess, Cushing's syndrome, develop a classic phenotype characteri...
The prevalences of insulin resistance and type 2 diabetes mellitus are rising dramatically, and, as ...
Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic e...
The studies described in this thesis were designed to evaluate the role of gastrointestinal hormones...
Dehydroepiandrosterone (DHEA) and glucocorticoids are steroid hormones synthesised in the adrenal co...
00073.2003.—A basis for the insulin mimetic effect of sphingomy-elinase on glucose transporter isofo...
Recent studies have demonstrated that fatty acids in-duce insulin resistance in skeletal muscle by b...
Peripheral insulin resistance (IR) is one of the main side effects caused by glucocorticoid (GC)-bas...
There are few and contradictory data on the role of excessive accumulation of intracellular sphingol...
Hypercortisolemia and glucocorticoid treatment cause elevated level of circulating free fatty acids ...
GLUT2 expression is strongly decreased in glucose-unresponsive pancreatic beta cells of diabetic rod...
Type 2 diabetes mellitus (T2DM) is a complex disease involving various physiological factors, hormon...
Glucocorticoid hormones constitute an integral component of the response to stress, and many of the ...
Polycystic ovary syndrome (PCOS) is a reproductive and metabolic disorder characterized by hyper...
Patients with glucocorticoid (GC) excess, Cushing's syndrome, develop a classic phenotype characteri...
Patients with glucocorticoid (GC) excess, Cushing's syndrome, develop a classic phenotype characteri...
The prevalences of insulin resistance and type 2 diabetes mellitus are rising dramatically, and, as ...
Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic e...
The studies described in this thesis were designed to evaluate the role of gastrointestinal hormones...
Dehydroepiandrosterone (DHEA) and glucocorticoids are steroid hormones synthesised in the adrenal co...
00073.2003.—A basis for the insulin mimetic effect of sphingomy-elinase on glucose transporter isofo...
Recent studies have demonstrated that fatty acids in-duce insulin resistance in skeletal muscle by b...
Peripheral insulin resistance (IR) is one of the main side effects caused by glucocorticoid (GC)-bas...
There are few and contradictory data on the role of excessive accumulation of intracellular sphingol...