Prevention of HIV infection through a vaccination strategy remains a high priority in the international and national community. More than 30 different vaccines have been used in limited clinical trials, and a large number of potential immunogens, such as inactivated whole virus and recombinant envelope and core HIV proteins, are in development or in clinical trials. Presently there are several phase III trials ongoing with promising agents, including the use of the env protein to induce both humoral and cell-mediated immunity. The genetic diversity of the HIV isolates creates real and potential difficulties in vaccine development, and the capability of the organism to mutate and create resistant isolates remains a great challenge. Ultimatel...
Despite an urgent need for a prophylactic vaccine against human immunodeficiency virus (HIV) type 1,...
One of the challenges facing HIV vaccine development is the diversity of the envelope protein (Env)....
A prophylactic vaccine for HIV-1 is badly needed. Despite 20 years of effort, it is still a long way...
Prevention of HIV infection through a vaccination strategy remains a high priority in the internatio...
Development of an effective AIDS vaccine is a global priority. However, the extreme diversity of HIV...
The goal of a prophylactic human immunodeficiency (HIV) vaccine is to elicit immune response(s) that...
Development of a preventive vaccine for HIV is the best hope of controlling the AIDS pandemic. HIV ...
The road to the discovery of a vaccine for HIV has been arduous and will continue to be difficult ov...
ABSTRACTAs the HIV pandemic continues, our best current treatments (reverse transcriptase inhibitors...
A human immunodeficiency virus (HIV) vaccine is the most promising and feasible strategy to prevent ...
In the global AIDS epidemic, over half of all infections have occurred in people less than 25 years ...
Forty years ago, the human immunodeficiency virus (HIV) pandemic began. It has since claimed the liv...
Lena J Gamble1, Qiana L Matthews1,21Division of Human Gene Therapy, Departments of Medicine, Patholo...
Almost four decades on, since the 1980’s, with hundreds of HIV vaccine candidates tested in both non...
An effective prophylactic HIV-1 vaccine is needed to eradicate the HIV/AIDS pandemic but designing s...
Despite an urgent need for a prophylactic vaccine against human immunodeficiency virus (HIV) type 1,...
One of the challenges facing HIV vaccine development is the diversity of the envelope protein (Env)....
A prophylactic vaccine for HIV-1 is badly needed. Despite 20 years of effort, it is still a long way...
Prevention of HIV infection through a vaccination strategy remains a high priority in the internatio...
Development of an effective AIDS vaccine is a global priority. However, the extreme diversity of HIV...
The goal of a prophylactic human immunodeficiency (HIV) vaccine is to elicit immune response(s) that...
Development of a preventive vaccine for HIV is the best hope of controlling the AIDS pandemic. HIV ...
The road to the discovery of a vaccine for HIV has been arduous and will continue to be difficult ov...
ABSTRACTAs the HIV pandemic continues, our best current treatments (reverse transcriptase inhibitors...
A human immunodeficiency virus (HIV) vaccine is the most promising and feasible strategy to prevent ...
In the global AIDS epidemic, over half of all infections have occurred in people less than 25 years ...
Forty years ago, the human immunodeficiency virus (HIV) pandemic began. It has since claimed the liv...
Lena J Gamble1, Qiana L Matthews1,21Division of Human Gene Therapy, Departments of Medicine, Patholo...
Almost four decades on, since the 1980’s, with hundreds of HIV vaccine candidates tested in both non...
An effective prophylactic HIV-1 vaccine is needed to eradicate the HIV/AIDS pandemic but designing s...
Despite an urgent need for a prophylactic vaccine against human immunodeficiency virus (HIV) type 1,...
One of the challenges facing HIV vaccine development is the diversity of the envelope protein (Env)....
A prophylactic vaccine for HIV-1 is badly needed. Despite 20 years of effort, it is still a long way...