The Multifocal VEP Is Abnormal in Regions of the Field Affected in Optic Neuritis

Multifocal visual evoked potentials (mVEP) and visual fields were obtained from patients who had experienced unilateral, acute optic neuritis. Although the traditionally recorded VEP generally shows reduced amplitude and delayed timing in such patients; it can be relatively normal in more than 20% of the cases. However, a mix of affected and unaffected regions can generate the traditional VEP. Here we examine local VEP changes