Neurofibromatosis Type 1 Associated Optic Glioma Visual Outcomes Following Chemotherapy: A Multi-center Retrospective Analysis

Optic gliomas (OPGs) arise in 15-20% of children with neurofibromatosis type 1 (NF1); nearly half become symptomatic. Much of the literature on treatment with chemotherapy has focused on radiographic outcomes. In contrast, despite nearly two decades of experience in treating NF1-associated OPG with chemotherapy, there is a paucity of information regarding the ophthalmologic outcome of these children.VBneurofibromatosison