Opsoclonus

Example of patients with opsoclonus, a saccadic abnormality. Discussion of characteristics of opsoclonus, such as involuntary, rapid, brief, random, conjugate saccades. Discussion of possible causes, including brain stem encephalitis (as in first patient), a paraneoplastic effect, tumors, and drug toxicity. Thought to be related to a disorder of the pause cells. Demonstration of obsoclonic movement being brought out by shifts in gaze. Demonstration of patient, whose lateral cerebellar hemispheric function is not too bad, performing finger-outstretched finger test.http://www.ncbi.nlm.nih.gov/pubmed?term=(+%22Opsoclonus-Myoclonus+Syndrome%2Fanalysis%22%5BMesh%5D+OR++%22Opsoclonus-Myoclonus+Syndrome%2Fanatomy+and+histology%22%5BMesh%5D+OR++%22Opsoclonus-Myoclonus+Syndrome%2Fdiagnosis%22%5BMesh%5D+OR++%22Opsoclonus-Myoclonus+Syndrome%2Fphysiology%22%5BMesh%5D+OR++%22Opsoclonus-Myoclonus+Syndrome%2Ftherapy%22%5BMesh%5D+)MTndosopsoclonu