Progressive Visual Loss in a Man with Leukemia

Lee, Michael

Publication date

February 2009

Publisher

Spencer S. Eccles Health Sciences Library, University of Utah

Abstract

Blurred vision OSA 48-year old male diagnosed with acute myeloid leukemia: Tx BMT.VA: Light perception OD, Hand motions OSMRIWhite matter vacuolization, axonal spheroids, macrophages in medulla and spinal cord.Myeloablative agonists1. Ding X, Herzligh AA, et al. Ocular toxicity of fludarabine: a purine analog. Expert Rev Ophthalmol. 2008;3:97-109. 2. Chun HG, Leyland-Jones, BR, et al. Central nervous system toxicity of fludarabine phosphate. Cancer Treat Rep. 1986;70:1225-28. 3. Warrell RP, Berman E. Phase I and II study of fludarabine phosphate in leukemia: therapeutic efficacy with delayed central nervous system toxicity. J Clin Oncol. 1986;4:74-79. 4. Cheson BD, Vena DA, et al. Neurotoxicity of purine analogs: a review. J Clin Oncol 1 99...