Howell-Jolly bodies in reticulocytes in peripheral blood smear (human)

Stain: May-Grnwald-Giemsa (MGG). The Howell-Jolly-bodies (1) in the reticulocyte are remnants of the nucleus (nuclear chromatin granules) of an erythroblast during anomalous development due to vitamin B12 deficiency, folic acid deficiency or in megaloblastic and hemolytic anemias. (2) Neutrophil with nuclear appendages. (3) Plasmacytoid lymphocyte (proliferating B cell) with bluish (basophilic) cytoplasm and a halo-zone. (4) Macrocytes with reduced central pallor