Neutrophilic granulocyte

Scheme electron microscopy. The neutrophil is a phagocytic cell (12-15 m) with a segmented lobular nucleus (3-5 lobes) and many cytoplasmic granules filled with degradative enzymes. These PMN cells (polymorph nuclear leukocytes) are the major cell types mediating acute inflammatory response to bacterial infections. The cytoplasm contains several types of granules (schematically only the two important types are depicted). (1) nuclear lobes; (2) Golgi area; (3) mitochondria; (4) secondary or specific granules; (5) lysosomes or primary granules. The neutrophilic granules are much smaller than the granules in eosinophils and basophils