Hemorrhagic septicemia - disease monograph series - 17

Most of the time vaccines for hemorrhagic septicemia (HS) do not match circulating strains of the virus, due to limited or lack of diagnostic and typing capacity, or do not include key components like leukotoxins. Cattle and buffalo are mainly affected. Vaccination of susceptible animals in endemic areas is the only practical approach to prevent HS. Although the available vaccines are effective in providing protection, disease outbreaks still occur due to low vaccination coverage, particularly of animals kept extensively. The paper presents detailed information on the incidence, prevalence and etiology of this infectious disease, as well as current vaccination possibilities.Bill & Melinda Gates FoundationGlobal Affairs Canad