Fusion of the viral and host cell membranes is a necessary first step for infection by enveloped viruses and is mediated by the envelope glycoprotein. The transmembrane subunits from the structurally defined class I glycoproteins adopt an α-helical trimer-of-hairpins conformation during the fusion pathway. Here, we present our studies on the envelope glycoprotein transmembrane subunit, GP2, of the CAS virus (CASV). CASV was recently identified from annulated tree boas (Corallus annulatus) with inclusion body disease and is implicated in the disease etiology. We have generated and characterized two protein constructs consisting of the predicted CASV GP2 core domain. The crystal structure of the CASV GP2 post-fusion conformation indicates...
The arenavirus envelope glycoprotein (GPC) retains a stable signal peptide (SSP) as an essential sub...
<div><p>Chandipura virus (CHAV), a member of the vesiculovirus genus, is an emerging human pathogen....
The arenavirus envelope glycoprotein (GPC) initiates infection in the host cell through pH-induced f...
Fusion of the viral and host cell membranes is a necessary first step for infection by enveloped vir...
Fusion of the viral and host cell membranes is a necessary first step for infection by enveloped vir...
Marburg virus (MARV) and Ebola virus (EBOV) constitute the family Filoviridae of enveloped viruses (...
Marburg virus (MARV) and Ebola virus (EBOV) are members of the family Filoviridae ( filoviruses ) an...
Marburg virus (MARV) and Ebola virus (EBOV) are members of the family <i>Filoviridae</i> (“filovirus...
The arenavirus envelope glycoprotein (GPC) retains a stable signal peptide (SSP) as an essential sub...
SummaryEnveloped viruses have developed various adroit mechanisms to invade their host cells. This p...
The emergence of Old and New World arenaviruses from rodent reservoirs persistently threatens human ...
An emergent viral pathogen termed ‘severe fever with thrombocytopenia syndrome virus’ (SFTSV) is res...
Enveloped viruses have developed various adroit mechanisms to invade their host cells. This process ...
An emergent viral pathogen termed severe fever with thrombocytopenia syndrome virus (SFTSV) is respo...
Arenaviruses comprise a diverse family of enveloped negative-strand RNA viruses that are endemic to ...
The arenavirus envelope glycoprotein (GPC) retains a stable signal peptide (SSP) as an essential sub...
<div><p>Chandipura virus (CHAV), a member of the vesiculovirus genus, is an emerging human pathogen....
The arenavirus envelope glycoprotein (GPC) initiates infection in the host cell through pH-induced f...
Fusion of the viral and host cell membranes is a necessary first step for infection by enveloped vir...
Fusion of the viral and host cell membranes is a necessary first step for infection by enveloped vir...
Marburg virus (MARV) and Ebola virus (EBOV) constitute the family Filoviridae of enveloped viruses (...
Marburg virus (MARV) and Ebola virus (EBOV) are members of the family Filoviridae ( filoviruses ) an...
Marburg virus (MARV) and Ebola virus (EBOV) are members of the family <i>Filoviridae</i> (“filovirus...
The arenavirus envelope glycoprotein (GPC) retains a stable signal peptide (SSP) as an essential sub...
SummaryEnveloped viruses have developed various adroit mechanisms to invade their host cells. This p...
The emergence of Old and New World arenaviruses from rodent reservoirs persistently threatens human ...
An emergent viral pathogen termed ‘severe fever with thrombocytopenia syndrome virus’ (SFTSV) is res...
Enveloped viruses have developed various adroit mechanisms to invade their host cells. This process ...
An emergent viral pathogen termed severe fever with thrombocytopenia syndrome virus (SFTSV) is respo...
Arenaviruses comprise a diverse family of enveloped negative-strand RNA viruses that are endemic to ...
The arenavirus envelope glycoprotein (GPC) retains a stable signal peptide (SSP) as an essential sub...
<div><p>Chandipura virus (CHAV), a member of the vesiculovirus genus, is an emerging human pathogen....
The arenavirus envelope glycoprotein (GPC) initiates infection in the host cell through pH-induced f...