NOD-like receptors (NLRs) play an important role in regulation of host innate immunity, yet their role in periodontitis remains to be defined. NLRX1, a member of the NLR family that localizes to mitochondria, modulates mitochondrial ROS (mROS) generation, which activates the NLRP3 inflammasome. However, the role of NLRX1 in NLRP3 inflammasome activation has not been examined. Therefore, we intend to investigate whether NLRX1 plays a role in NLRP3 inflammasome activation in periodontitis
Among a number of innate receptors, the nucleotide-binding domain leucine-rich repeat containing (NL...
The nod-like receptor protein 3 (NLRP3) inflammasome drives inflammation in response to mitochondria...
Recognition of pathogen-associated molecular patterns that activate IL-1b is regulated by inflammaso...
NOD-like receptors (NLRs) play an important role in regulation of host innate immunity, yet their ro...
NOD-like receptors (NLRs) play a significant role in regulation of host innate immunity, yet their r...
NOD-like receptors (NLRs) play a large role in regulation of host innate immunity, yet their role in...
Periodontitis, a chronic inflammatory disease results from both dysbiotic microbiota and dysregulate...
Regulatory Nod-like receptors (NLRs) are a subgroup of the cytosolic NLR family of pathogen recognit...
A major function of a subfamily of NLR (nucleotide-binding domain, leucine rich repeat containing or...
A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, o...
NLRX1 is a recently characterized member of the intracellular family of Nod-like receptors (NLRs), a...
SummaryTight regulation of NF-κB signaling is essential for innate and adaptive immune responses, ye...
International audienceThe NLRP3 inflammasome is overexpressed in gingiva of periodontitis patients b...
SummaryThe nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate inna...
Porphyromonas gingivalis, a major periodontopathogen, is involved in the pathogenesis of periodontit...
Among a number of innate receptors, the nucleotide-binding domain leucine-rich repeat containing (NL...
The nod-like receptor protein 3 (NLRP3) inflammasome drives inflammation in response to mitochondria...
Recognition of pathogen-associated molecular patterns that activate IL-1b is regulated by inflammaso...
NOD-like receptors (NLRs) play an important role in regulation of host innate immunity, yet their ro...
NOD-like receptors (NLRs) play a significant role in regulation of host innate immunity, yet their r...
NOD-like receptors (NLRs) play a large role in regulation of host innate immunity, yet their role in...
Periodontitis, a chronic inflammatory disease results from both dysbiotic microbiota and dysregulate...
Regulatory Nod-like receptors (NLRs) are a subgroup of the cytosolic NLR family of pathogen recognit...
A major function of a subfamily of NLR (nucleotide-binding domain, leucine rich repeat containing or...
A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, o...
NLRX1 is a recently characterized member of the intracellular family of Nod-like receptors (NLRs), a...
SummaryTight regulation of NF-κB signaling is essential for innate and adaptive immune responses, ye...
International audienceThe NLRP3 inflammasome is overexpressed in gingiva of periodontitis patients b...
SummaryThe nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate inna...
Porphyromonas gingivalis, a major periodontopathogen, is involved in the pathogenesis of periodontit...
Among a number of innate receptors, the nucleotide-binding domain leucine-rich repeat containing (NL...
The nod-like receptor protein 3 (NLRP3) inflammasome drives inflammation in response to mitochondria...
Recognition of pathogen-associated molecular patterns that activate IL-1b is regulated by inflammaso...