Aspiration of bile into the cystic fibrosis (CF) lung has emerged as a prognostic factor for reduced microbial lung biodiversity and the establishment of often fatal, chronic pathogen infections. Staphylococcus aureus is one of the earliest pathogens detected in the lungs of children with CF, and once established as a chronic infection, strategies for its eradication become limited. Several lung pathogens are stimulated to produce biofilms in vitro in the presence of bile. In this study, we further investigated the effects of bile on S. aureus biofilm formation. Most clinical S. aureus strains and the laboratory strain RN4220 were stimulated to form biofilms with sub-inhibitory concentrations of bovine bile. Additionally, we observed bile-i...
Introduction: Staphylococcus aureus is one of the first bacteria colonizing in cystic fibrosis (CF) ...
In the current study, we show that biofilm formation by various strains and species belonging to Bif...
Salmonella enterica serovar Typhi can establish a chronic, asymptomatic infection of the human gallb...
Aspiration of bile into the cystic fibrosis (CF) lung has emerged as a prognostic factor for reduced...
Despite aggressive antimicrobial therapy, many respiratory pathogens persist in the lung, underpinni...
The opportunistic pathogen Pseudomonas aeruginosa is the leading cause of morbidity and mortality in...
<p>Addition of subinhibitory concentrations of bile (0.3%) significantly increased biofilm formation...
<div><p>Chronic respiratory infections are a major cause of morbidity and mortality, most particular...
Staphylococcus aureus is a major human pathogen whose characteristics support its success in various...
Cystic fibrosis (CF) is a life-threatening, inherited, multi-organ disease that renders patients sus...
The study of the respiratory microbiota has revealed that the lungs of healthy and diseased individu...
Chronic respiratory infections are a leading global cause of morbidity and mortality. However, the m...
<p>Bile aspiration linked to GER is highly prevalent in CF patients and has been linked to reduced p...
Cystic fibrosis (CF) is a life-threatening, inherited, multi-organ disease that renders patients sus...
The colonization of Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), has a ...
Introduction: Staphylococcus aureus is one of the first bacteria colonizing in cystic fibrosis (CF) ...
In the current study, we show that biofilm formation by various strains and species belonging to Bif...
Salmonella enterica serovar Typhi can establish a chronic, asymptomatic infection of the human gallb...
Aspiration of bile into the cystic fibrosis (CF) lung has emerged as a prognostic factor for reduced...
Despite aggressive antimicrobial therapy, many respiratory pathogens persist in the lung, underpinni...
The opportunistic pathogen Pseudomonas aeruginosa is the leading cause of morbidity and mortality in...
<p>Addition of subinhibitory concentrations of bile (0.3%) significantly increased biofilm formation...
<div><p>Chronic respiratory infections are a major cause of morbidity and mortality, most particular...
Staphylococcus aureus is a major human pathogen whose characteristics support its success in various...
Cystic fibrosis (CF) is a life-threatening, inherited, multi-organ disease that renders patients sus...
The study of the respiratory microbiota has revealed that the lungs of healthy and diseased individu...
Chronic respiratory infections are a leading global cause of morbidity and mortality. However, the m...
<p>Bile aspiration linked to GER is highly prevalent in CF patients and has been linked to reduced p...
Cystic fibrosis (CF) is a life-threatening, inherited, multi-organ disease that renders patients sus...
The colonization of Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), has a ...
Introduction: Staphylococcus aureus is one of the first bacteria colonizing in cystic fibrosis (CF) ...
In the current study, we show that biofilm formation by various strains and species belonging to Bif...
Salmonella enterica serovar Typhi can establish a chronic, asymptomatic infection of the human gallb...