Add to ORKGWe tested the hypothesis that irregular menstruation predicts lower risk for ovarian cancer, possibly due to less frequent ovulation. We conducted a 50-year prospective study of 15,528 mothers in the Child Health and Development Studies cohort recruited from the Kaiser Foundation Health Plan from 1959 to 1966. Irregular menstruation was classified via medical record and self-report at age 26. We identified 116 cases and 84 deaths due to ovarian cancer through 2011 via linkage to the California Cancer Registry and Vital Statistics. Contrary to expectation, women with irregular menstrual cycles had a higher risk of ovarian cancer incidence and mortality over the 50-year follow-up. Associations increased with age (p <0.05). We observed a 2-fol...
Ovarian cancer etiology is not fully elucidated and few modifiable risk factors have been identified...
Serous, endometrioid, clear cell and mucinous histotypes are the most common epithelial ovarian canc...
Parity, oral contraceptive use, and hysterectomy are known to protect against ovarian cancer, wherea...
We tested the hypothesis that irregular menstruation predicts lower risk for ovarian cancer, possibl...
Introduction: Early age at menarche and late age at last menstrual period, as well as other reproduc...
The relationship between menstrual factors and the risk of ovarian cancer was evaluated in the frame...
Repeated exposure to the acute proinflammatory environment that follows ovulation at the ovarian sur...
Repeated exposure to the acute proinflammatory environment that follows ovulation at the ovarian sur...
Background: Polycystic ovary syndrome (PCOS), and one of its distinguishing characteristics, oligome...
Background: The location of the ovaries makes it difficult to diagnose ovarian cancer at an earlier ...
There has been much progress in ovarian cancer screening and prevention in recent years. Improved to...
Objective: Several factors that are related to ovulation are relevant to ovarian cancer risk, but it...
Menstrual cycle characteristics and ovulatory infertility were evaluated in relation to breast cance...
Repeated exposure to the acute proinflammatory environment that follows ovulation at the ovarian sur...
Ovarian cancer is most frequently diagnosed in postmenopausal women; however, the strongest risk pre...
Ovarian cancer etiology is not fully elucidated and few modifiable risk factors have been identified...
Serous, endometrioid, clear cell and mucinous histotypes are the most common epithelial ovarian canc...
Parity, oral contraceptive use, and hysterectomy are known to protect against ovarian cancer, wherea...
We tested the hypothesis that irregular menstruation predicts lower risk for ovarian cancer, possibl...
Introduction: Early age at menarche and late age at last menstrual period, as well as other reproduc...
The relationship between menstrual factors and the risk of ovarian cancer was evaluated in the frame...
Repeated exposure to the acute proinflammatory environment that follows ovulation at the ovarian sur...
Repeated exposure to the acute proinflammatory environment that follows ovulation at the ovarian sur...
Background: Polycystic ovary syndrome (PCOS), and one of its distinguishing characteristics, oligome...
Background: The location of the ovaries makes it difficult to diagnose ovarian cancer at an earlier ...
There has been much progress in ovarian cancer screening and prevention in recent years. Improved to...
Objective: Several factors that are related to ovulation are relevant to ovarian cancer risk, but it...
Menstrual cycle characteristics and ovulatory infertility were evaluated in relation to breast cance...
Repeated exposure to the acute proinflammatory environment that follows ovulation at the ovarian sur...
Ovarian cancer is most frequently diagnosed in postmenopausal women; however, the strongest risk pre...
Ovarian cancer etiology is not fully elucidated and few modifiable risk factors have been identified...
Serous, endometrioid, clear cell and mucinous histotypes are the most common epithelial ovarian canc...
Parity, oral contraceptive use, and hysterectomy are known to protect against ovarian cancer, wherea...