Add to ORKGHospitalized preterm infants receive frequent and often prolonged exposures to antibiotics because they are vulnerable to infection. It is not known whether the short-term effects of antibiotics on the preterm infant gut microbiota and resistome persist after discharge from neonatal intensive care units. Here, we use complementary metagenomic, culture-based and machine learning techniques to study the gut microbiota and resistome of antibiotic-exposed preterm infants during and after hospitalization, and we compare these readouts to antibiotic-naive healthy infants sampled synchronously. We find a persistently enriched gastrointestinal antibiotic resistome, prolonged carriage of multidrug-resistant Enterobacteriaceae and distinct antibiotic...
The assembly and development of the gut microbiome in infants have important consequences for immedi...
IntroductionThe infant gut microbiome is thought to play a key role in developing metabolic and immu...
Immediately after birth, newborn babies experience rapid colonisation by microorganisms from their m...
Background: Few studies have investigated the gut microbiome of infants, fewer still preterm infants...
Preterm infants suffer from a higher incidence of acute diseases such as necrotising enterocolitis a...
Background The preterm microbiome is crucial to gut health and may contribute to necrotising enteroc...
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have pronounced eff...
Background Infants are at a high risk of acquiring fatal infections, and their treatment relies on f...
AbstractPreterm infants in a neonatal intensive care unit (NICU) are exposed to multidrug-resistant ...
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have pronounced eff...
Abstract Background The human gut microbiome harbors a collection of bacterial antimicrobial resista...
Background: The source inoculum of gastrointestinal tract (GIT) microbes is largely influenced by de...
BackgroundAntibiotic-resistant (AR) bacteria are a global threat. AR bacteria can be acquired in ear...
Prematurity exposes newborns to increased risks of infections and it is associated with critical mor...
The gut bacterial community plays a vital role in human health with a diverse and complex compositio...
The assembly and development of the gut microbiome in infants have important consequences for immedi...
IntroductionThe infant gut microbiome is thought to play a key role in developing metabolic and immu...
Immediately after birth, newborn babies experience rapid colonisation by microorganisms from their m...
Background: Few studies have investigated the gut microbiome of infants, fewer still preterm infants...
Preterm infants suffer from a higher incidence of acute diseases such as necrotising enterocolitis a...
Background The preterm microbiome is crucial to gut health and may contribute to necrotising enteroc...
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have pronounced eff...
Background Infants are at a high risk of acquiring fatal infections, and their treatment relies on f...
AbstractPreterm infants in a neonatal intensive care unit (NICU) are exposed to multidrug-resistant ...
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have pronounced eff...
Abstract Background The human gut microbiome harbors a collection of bacterial antimicrobial resista...
Background: The source inoculum of gastrointestinal tract (GIT) microbes is largely influenced by de...
BackgroundAntibiotic-resistant (AR) bacteria are a global threat. AR bacteria can be acquired in ear...
Prematurity exposes newborns to increased risks of infections and it is associated with critical mor...
The gut bacterial community plays a vital role in human health with a diverse and complex compositio...
The assembly and development of the gut microbiome in infants have important consequences for immedi...
IntroductionThe infant gut microbiome is thought to play a key role in developing metabolic and immu...
Immediately after birth, newborn babies experience rapid colonisation by microorganisms from their m...