In the frame of the materialist movement “New Wave Reductionism”, in the last decade, the idea of “Ruthless Reductionism” presented by the philosopher John Bickle in his book “Philosophy and Neuroscience: a ruthlessly reductive account” (2003) had a major impact producing a wave of researches interlinking philosophy and neuroscience, which contents vary between protocols and experimental designs, causality, mechanisms and multiple realizations. This paper is intended to present John Bickle‟s model (1998, 2003, 2006) within this movement. Furthermore, it includes a review of two authors: Jaquelline Sullivan (2008, 2008) and Ken Aizawa (2007, 2008), with the purpose of examining the mentioned model and raising the main critiques that have bee...