In order to elucidate the question whether resistance to nitro drugs in G. lamblia is due to common resistance markers, trophozoites of three resistant G. lamblia strains, namely C4, 1062ID10, and 713M3 were grown in the presence of the two nitro drugs metronidazole and nitazoxanide and compared to their corresponding wild-types WBC6, 106, and 713 by mass spectometry shotgun analysis of their proteomes. Depending on the strain and the nitro drug, more than 200 to 500 differentially expressed proteins were identified, but there were no common patterns across strains and drugs. All resistant strains underwent antigenic variation with distinct surface antigens like variant surface proteins or cysteine rich proteins depending on strain and nitr...
OBJECTIVES The characterization of differential gene expression in Giardia lamblia WB C6 strain C...
Background: Metronidazole (Mtz) is the frontline drug treatment for multiple anaerobic pathogens, in...
AbstractGiardia lamblia is a protozoan parasite that causes giardiasis, a diarrhoeal disease affecti...
In order to elucidate the question whether resistance to nitro drugs in G. lamblia is due to common ...
For over 50 years, metronidazole and other nitro compounds such as nitazoxanide have been used as a ...
Objectives The characterization of Giardia lamblia WB C6 strains resistant to metronidazole and to t...
Objectives The protozoan parasite Giardia lamblia causes giardiasis, a persistent diarrhoea. Nitro d...
Giardia lamblia is a causative agent of persistent diarrhoea widespread in regions with low hygienic...
Objectives The protozoan parasite Giardia lamblia causes the intestinal disease giardiasis, which ma...
Objectives The characterization of differential gene expression in Giardia lamblia WB C6 strain C4 r...
OBJECTIVES The protozoan parasite Giardia lamblia causes giardiasis, a persistent diarrhoea. Nitr...
Purpose: Treatment-refractory Giardia cases have increased rapidly within the last decade. No marker...
The effectiveness of metronidazole against the tetraploid intestinal parasite Giardia lamblia is dep...
Giardia duodenalis is an intestinal parasite that causes 200-300 million episodes of diarrhoea annua...
Purpose: Treatment-refractory Giardia cases have increased rapidly within the last decade. No marker...
OBJECTIVES The characterization of differential gene expression in Giardia lamblia WB C6 strain C...
Background: Metronidazole (Mtz) is the frontline drug treatment for multiple anaerobic pathogens, in...
AbstractGiardia lamblia is a protozoan parasite that causes giardiasis, a diarrhoeal disease affecti...
In order to elucidate the question whether resistance to nitro drugs in G. lamblia is due to common ...
For over 50 years, metronidazole and other nitro compounds such as nitazoxanide have been used as a ...
Objectives The characterization of Giardia lamblia WB C6 strains resistant to metronidazole and to t...
Objectives The protozoan parasite Giardia lamblia causes giardiasis, a persistent diarrhoea. Nitro d...
Giardia lamblia is a causative agent of persistent diarrhoea widespread in regions with low hygienic...
Objectives The protozoan parasite Giardia lamblia causes the intestinal disease giardiasis, which ma...
Objectives The characterization of differential gene expression in Giardia lamblia WB C6 strain C4 r...
OBJECTIVES The protozoan parasite Giardia lamblia causes giardiasis, a persistent diarrhoea. Nitr...
Purpose: Treatment-refractory Giardia cases have increased rapidly within the last decade. No marker...
The effectiveness of metronidazole against the tetraploid intestinal parasite Giardia lamblia is dep...
Giardia duodenalis is an intestinal parasite that causes 200-300 million episodes of diarrhoea annua...
Purpose: Treatment-refractory Giardia cases have increased rapidly within the last decade. No marker...
OBJECTIVES The characterization of differential gene expression in Giardia lamblia WB C6 strain C...
Background: Metronidazole (Mtz) is the frontline drug treatment for multiple anaerobic pathogens, in...
AbstractGiardia lamblia is a protozoan parasite that causes giardiasis, a diarrhoeal disease affecti...