Thiol ene click chemistry towards easy microarraying of half-antibodies

[EN] A UV light-induced thiol-ene coupling reaction (TEC) between half-antibodies (hIgG) and vinyl functionalized glass surfaces was run for biosensing in the microarray format. The accomplished performance improved that obtained with whole antibodies.The authors acknowledge the funding from the European Commission through the project H2020-634013-PHOCNOSIS. This work was also partly supported by MINECO CTQ/2013/45875-R, CTQ/2016/75749-R, FEDER, and GVA PROMETEO II 2014/40.Alonso Ruiz, R.; Jimenez-Meneses, P.; García-Rupérez, J.; Bañuls Polo, M.; Maquieira Catala, A. (2018). Thiol ene click chemistry towards easy microarraying of half-antibodies. Chemical Communications. 54(48):6144-6147. https://doi.org/10.1039/c8cc01369a61446147544