Extraction of β-sitosterol from Swietenia mahagoni seeds by using supercritical carbon dioxide (SC-CO2) extraction

This work investigates the effect of supercritical carbon dioxide (SC-CO2) extraction conditions (pressure and temperature) on the oil yield and β-sitosterol content extracted from Swietenia mahagoni seeds by using response surface methodology (RSM). The experimental data obtained were fitted to a second-order polynomial model and the obtained oil yields were 1.49-14.45%, while β-sitosterol content obtained were 3.12-9.20 mg/g. The best conditions within the ranges studied were 30 MPa and 40°C to extract β-sitosterol in the highest amount. The present findings show that S. mahagoni seeds extract has a high concentration of β-sitosterol