Andrea M Eisenbeis, Stefan J GrauDepartment of Neurosurgery, University Hospital of Cologne, Cologne, GermanyAbstract: Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragments in various fields in medicine. In this context, a rapidly growing number of these substances have also emerged in the field of oncology. This review will summarize the currently approved monoclonal antibodies used for the treatment of solid tumors with a focus on their clinical application, biological background, and currently ongoing trials.Keywords: targeted therapy, monoclonal antibodies, cancer, biolo...
Abstract In the last two decades there is substantial development in the diagnostic and therapy of m...
As hematological malignancies are a growing concern, more targeted chemotherapy options are being in...
SUMMARY Molecular biology has made tremendous strides over the last five years. The new biology allo...
Introduction: The use of monoclonal antibodies is one of the strategies for targeting the specific k...
Monoclonal antibodies (mAbs) have become a cornerstone in the therapeutic guidelines of a wide range...
Introduction: The use of monoclonal antibodies is one of the strategies for targeting the specific k...
Therapeutic monoclonal antibodies have emerged in the 1990 decade as an important option for cancer ...
The growing understanding of the molecular mechanisms of carcinogenesis accelerated the development ...
During the past 20 years, dozens—if not hundreds—of monoclonal antibodies have been developed and ch...
In recent years, monoclonal antibodies have become important weapons in the arsenal of anticancer dr...
The use of anti-human signal molecules monoclonal antibod-ies (mAbs) for malignant tumors therapy ha...
Much progress has been made during the last few decades in the treatment of malignancies. Many types...
The recent approval of cetuximab and bevacizumab by FDA for the treatment of metastatic colore...
Monoclonal antibodies are at the forefront of novel therapeutic strategies for cancer and have made ...
In view of the explosion of the present clinical use of monoclonal antibodies (mAbs), not only in th...
Abstract In the last two decades there is substantial development in the diagnostic and therapy of m...
As hematological malignancies are a growing concern, more targeted chemotherapy options are being in...
SUMMARY Molecular biology has made tremendous strides over the last five years. The new biology allo...
Introduction: The use of monoclonal antibodies is one of the strategies for targeting the specific k...
Monoclonal antibodies (mAbs) have become a cornerstone in the therapeutic guidelines of a wide range...
Introduction: The use of monoclonal antibodies is one of the strategies for targeting the specific k...
Therapeutic monoclonal antibodies have emerged in the 1990 decade as an important option for cancer ...
The growing understanding of the molecular mechanisms of carcinogenesis accelerated the development ...
During the past 20 years, dozens—if not hundreds—of monoclonal antibodies have been developed and ch...
In recent years, monoclonal antibodies have become important weapons in the arsenal of anticancer dr...
The use of anti-human signal molecules monoclonal antibod-ies (mAbs) for malignant tumors therapy ha...
Much progress has been made during the last few decades in the treatment of malignancies. Many types...
The recent approval of cetuximab and bevacizumab by FDA for the treatment of metastatic colore...
Monoclonal antibodies are at the forefront of novel therapeutic strategies for cancer and have made ...
In view of the explosion of the present clinical use of monoclonal antibodies (mAbs), not only in th...
Abstract In the last two decades there is substantial development in the diagnostic and therapy of m...
As hematological malignancies are a growing concern, more targeted chemotherapy options are being in...
SUMMARY Molecular biology has made tremendous strides over the last five years. The new biology allo...