The effect of ketamine on sore throat after tonsillectomy

AbstractBackground and purpose: Ketamine efficacy as an analgesic adjuvant has been studied in several clinical settings with conflicting results. Sore throat and pain after swallowing following tonsillectomy is significant. The aim of this study was to investigate the effect of ketamine on sore throat (pain) after tonsillectomy.Materials and Methods: In this double blind clinical trial, fifty children were, divided in to two equal groups of Ketamine and control. The subjects aged 4-14 years old and physical ASA class I-II were randomized to receive pemedication with either ketamine 0.1mg/kg I.V. or placebo 5 minutes before induction of a standard general anesthesia.Results: The ketamine group showed significantly lower pain scores with less total pethidine consumption (P