Add to ORKGGermline mutations of BRCA1 predispose women to breast and ovarian cancers. Elucidating molecular mechanism of tissue- and gender-specific phenomena in BRCA1-related tumors is a key to our understanding of BRCA1 function in tumor suppression. This review summarizes studies in recent years on the link between BRCA1 and estrogen/progesterone signaling pathways, as well as discusses various models underscoring a triangle relationship among BRCA1, estrogen and genome instability.</p
Ovarian cancer is the most lethal cause of death from gynecological malignancies in the Western worl...
Objective. BRCA1 mutations predispose to cancer in hormone responsive tissues. A predominance of est...
Germ-line mutations in breast cancer susceptibility gene 1 (BRCA1) predominantly predispose women to...
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that th...
The breast and ovarian cancer susceptibility gene-1 (BRCA1) located on chromosome 17q21 encodes a tu...
International audienceWomen with inherited BRCA1 mutations have an elevated risk (40-80%) for develo...
International audienceWomen with inherited BRCA1 mutations have an elevated risk (40-80%) for develo...
Zsuzsanna Suba Surgical and Molecular Tumor Pathology Centre, National Institute of Oncology, Budap...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Restricted until 1 July 2010.The exact mechanism by which Breast Cancer Susceptibility Gene1 (BRCA1)...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Mutations within the BRCA1 tumor suppressor gene occur frequently in familial epithelial ovarian car...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Breast cancer susceptibility gene 1 () is a tumor suppressor gene, which is mainly involved in the r...
Ovarian cancer is the most lethal cause of death from gynecological malignancies in the Western worl...
Objective. BRCA1 mutations predispose to cancer in hormone responsive tissues. A predominance of est...
Germ-line mutations in breast cancer susceptibility gene 1 (BRCA1) predominantly predispose women to...
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that th...
The breast and ovarian cancer susceptibility gene-1 (BRCA1) located on chromosome 17q21 encodes a tu...
International audienceWomen with inherited BRCA1 mutations have an elevated risk (40-80%) for develo...
International audienceWomen with inherited BRCA1 mutations have an elevated risk (40-80%) for develo...
Zsuzsanna Suba Surgical and Molecular Tumor Pathology Centre, National Institute of Oncology, Budap...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Restricted until 1 July 2010.The exact mechanism by which Breast Cancer Susceptibility Gene1 (BRCA1)...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Mutations within the BRCA1 tumor suppressor gene occur frequently in familial epithelial ovarian car...
Germline mutations in BRCA1 predispose carriers to a high incidence of breast and ovarian cancers. B...
Breast cancer susceptibility gene 1 () is a tumor suppressor gene, which is mainly involved in the r...
Ovarian cancer is the most lethal cause of death from gynecological malignancies in the Western worl...
Objective. BRCA1 mutations predispose to cancer in hormone responsive tissues. A predominance of est...
Germ-line mutations in breast cancer susceptibility gene 1 (BRCA1) predominantly predispose women to...