Add to ORKGBackground: Hemoglobinopathy and thalassemia are prevalent genetic disorders throughout the world. Beta thalassemia is one of these disorders with high prevalence in Iran, especially in Khuzestan province. In this study, the rate of different mutations in β-globin gene for prenatal diagnosis in fetal samples was evaluated.Materials and methods: In this experimental pilot study, 316 fetal samples (chorionic villus or amniotic fluid) suspicious to hemoglobin disorders were enrolled. Afterwards, DNA was extracted and PCR and DNA sequencing were used for evaluation of different mutations in β-globin gene.Results: Amongst 316 samples evaluated for prenatal diagnosis, 180 cases (56.8%) were carrying at least one mutated gene of β-thalassemia. In ...
Background: The molecular defects resulting in β-thalassemia phenotype, in the Egyptian population s...
Forty-seven Chinese suffering from β thalassemia major and their parents were studied to establish l...
The primary aim of this thesis was to outline an approach for the prenatal diagnosis of β-thalassaem...
Background: Hemoglobinopathy and thalassemia are prevalent genetic disorders throughout the world. B...
Background: Mutations in β-globin gene may result in β-thalassemia major, which is one of the most c...
Abstract Background Beta-thalassemia is common in the Mediterranean area as well as the Middle East ...
Background and objective: ß-thalassemia results from a diverse range of mutations inside the hemoglo...
Background and purpose : bata thlassemia is the most common monogenic disorders in Iran. The gene fr...
beta-Thalassemia is the most common genetic disorder in Pakistan, where more than 6000 affected chil...
β thalassaemia is defined as a group of heterogeneous anaemias in which the β globin peptide synthes...
Background : The hemoglobinopathies refer to a diverse group of inherited disorders characterized by...
Background: β-thalassemia is a common autosomal recessive disorder resulting from over 200 different...
Objectives: Thalassemia is the most common single gene disorder and is widely distributed in Asian I...
Introduction: Recent molecular studies on Iranian β-thalassemia genes revealed the presence of eight...
Background: To study the effectiveness of choronic villous sampling, followed by molecular analysis,...
Background: The molecular defects resulting in β-thalassemia phenotype, in the Egyptian population s...
Forty-seven Chinese suffering from β thalassemia major and their parents were studied to establish l...
The primary aim of this thesis was to outline an approach for the prenatal diagnosis of β-thalassaem...
Background: Hemoglobinopathy and thalassemia are prevalent genetic disorders throughout the world. B...
Background: Mutations in β-globin gene may result in β-thalassemia major, which is one of the most c...
Abstract Background Beta-thalassemia is common in the Mediterranean area as well as the Middle East ...
Background and objective: ß-thalassemia results from a diverse range of mutations inside the hemoglo...
Background and purpose : bata thlassemia is the most common monogenic disorders in Iran. The gene fr...
beta-Thalassemia is the most common genetic disorder in Pakistan, where more than 6000 affected chil...
β thalassaemia is defined as a group of heterogeneous anaemias in which the β globin peptide synthes...
Background : The hemoglobinopathies refer to a diverse group of inherited disorders characterized by...
Background: β-thalassemia is a common autosomal recessive disorder resulting from over 200 different...
Objectives: Thalassemia is the most common single gene disorder and is widely distributed in Asian I...
Introduction: Recent molecular studies on Iranian β-thalassemia genes revealed the presence of eight...
Background: To study the effectiveness of choronic villous sampling, followed by molecular analysis,...
Background: The molecular defects resulting in β-thalassemia phenotype, in the Egyptian population s...
Forty-seven Chinese suffering from β thalassemia major and their parents were studied to establish l...
The primary aim of this thesis was to outline an approach for the prenatal diagnosis of β-thalassaem...