HBV/HCV重叠感染的研究进展

Hepatitis B virus (HBV) is a hepatotropic DNA virus; HBV DNA and special P protein are covered by capsid proteins to form core particles, which are then covered by lipoprotein to form complete virus particles. Hepatitis C virus (HCV), which belongs to the Flaviviridae family, is a single-stranded, positive-sense RNA. HBV and HCV are transmitted by parenteral route and may cause co-infection through the same route of transmission. The pathogenesis of HBV/HCV co-infection and its relationship with occult HBV infection, hepatocellular carcinoma, organ transplantation, and HBV vaccine are reviewed. Meanwhile, the treatment of co-infection is presented. It is shown that HBV and HCV interfere with each other in terms of virology and pathology