International audienceIn order to study climate variations during the last 1700 years in eastern France, fifty-eight oxygen isotope compositions of phosphate were measured in human tooth enamel. The individuals, who lived in Lorraine, are assumed to have drunk local water derived directly from rainfall. According to previous work, drinking water is the main source of oxygen that sets the isotopic composition of phosphatic tissues in humans. The empirical fractionation equation determined from our data combined with those of Longinelli's one [Geochim. Cosmochim. Acta 48 (1984) 385] was used to calculate the oxygen isotope composition of meteoric waters. The mean air temperature was inferred from these isotope ratios and the Von Grafenstein e...