Increasing Trend of Non-Interventional Treatment Management in Patients Candidate to Active Surveillance with Localized Prostate Cancer

Introduction & Objectives: The rate of non-interventional treatment (NIT) in prostate cancer (PCa) active surveillance (AS) candidates were shown to be on the rise. However, contemporary data have not been reported. To address this void, we examined NIT rate between 2010-2014, within 16 Surveillance Epidemiology and End Results (SEER) registries. Materials & Methods: We identified 21,398 PCa patients that fulfilled the University of California, San Francisco AS criteria (prostate specific antigen [PSA] \u3c10ng/ml, clinical T stage 4ng/ml, cT2a and \u3e1 positive core) only the proportion of NIT patients aged Conclusions: The rate of NIT as markedly increased across all examined SEER-registries. Nonetheless, very important differences distinguish high-hand NIT users from low-hand NIT users. PCa characteristics of NIT patients remained unchanged overtime. However, in addition to geographical differences in NIT rates, patient characteristic such as age, marital and insurance status represent potential barriers