Chemistry has acquired a high relevance on human life; therefore, it is imperative to think about aspects that involve its paradigm, and on its autonomy facing other natural sciences. In order to justify this autonomy, a starting point to take into account is the conceptual frame derived from the periodic system of the chemical elements. In the present outreach article, a systematic exposition of this and other aspects is performed, that justifying and configuring a philosophy of chemistry, as a field immersed in the philosophy of science, that generates the most ideal space for the attentive consideration on the fundamental aspects of chemistry such as, reconciliation between nominalism and realism, methodology, linguistic, history, and et...