Histopatologic Evaluation of the Effect of Advanced Periodontal Diseases on Pulp Tissue

Introduction: The diagnosis of the origin of the lesions is one of the basic problems in Endo-Perio lesion. In order to prevent unnecessary and harmful treatment, the accurate diagnosis must be developed. The aim of this study was to evaluate the effect of advanced periodontal diseases on pulp tissue.Methods and materials: In this experimental study, fourty two anterior teeth were extracted from 22 patients referred to dental clinic of Isfahan university with advanced periodontal disease and 5 intact teeth as control were sectioned immediately after extraction. Teeth were fixed in 10% formalin solution. They were decalcified with Nitric Acid 10% and finally two histopathologic sections were prepared and evaluated. The results were statistically analyzed by Fisher’s exact test.Results: From total of 42 teeth; 13 teeth had normal pulp (30.95%), and the other 29 teeth (69.05%) had pulpal problem. The control group showed 100% normal results. Statistical analysis of the results showed significant difference between two groups.Conclusion: Under the limitations of the present study it was concluded that periodontal disease can develop inflammatory lesions, atrophic and degenerative changes in pulp