Objective: To determine the association between BRCA1 gene Q356R (1186A=G) polymorphism and epithelial ovarian cancer incidence. Methods: This study is an observational analytic study with casecontrol study design. All patients diagnosed with epithelial ovarian cancer that were treated in the outpatient clinic and inpatient ward of the Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin Hospital, Palembang who met the inclusion criteria were included in this study. DNA extraction was performed on blood samples, followed by PCR-RFLP process. Results: We obtained the genotype distribution of BRCA1 Q356R (1186A=G) polymorphisms to be QQ genotype (wild-type) on all 50 subjects in the case group (100%) and 50 control subjects (100%). Si...
Epithelial ovarian cancer (EOC) is a heterogeneous disease with a major heritable component. The dif...
BACKGROUND:Recent studies have identified several single nucleotide polymorphisms (SNPs) in the popu...
We report a novel BRCA1 germline 4156delAA mutation detected in a 41-year-old woman with breast and ...
Objective: To determine the association between BRCA1 gene Q356R (1186A=G) polymorphism and epithel...
OBJECTIVES: Mutations in the BRCA1 and BRCA2 genes predispose women to ovarian and/or breast cancer....
The value of identifying women with an inherited predisposition to epithelial ovarian cancer has bec...
The objective of this study was to provide more accurate frequency estimates of breast cancer suscep...
SummaryWe conducted a population-based study to determine the contribution of germline mutations in ...
A population-based series of 649 unselected incident cases of ovarian cancer diagnosed in Ontario, C...
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian canc...
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian canc...
The objective of this study was to determine the prevalence of BRCA1 and BRCA2 gene mutations in uns...
Ovarian cancer is the most common cause of death from gynecological cancers in the Western world. Th...
Epithelial ovarian cancer (EOC) is a heterogeneous disease with a major heritable component. The dif...
BACKGROUND:Recent studies have identified several single nucleotide polymorphisms (SNPs) in the popu...
We report a novel BRCA1 germline 4156delAA mutation detected in a 41-year-old woman with breast and ...
Objective: To determine the association between BRCA1 gene Q356R (1186A=G) polymorphism and epithel...
OBJECTIVES: Mutations in the BRCA1 and BRCA2 genes predispose women to ovarian and/or breast cancer....
The value of identifying women with an inherited predisposition to epithelial ovarian cancer has bec...
The objective of this study was to provide more accurate frequency estimates of breast cancer suscep...
SummaryWe conducted a population-based study to determine the contribution of germline mutations in ...
A population-based series of 649 unselected incident cases of ovarian cancer diagnosed in Ontario, C...
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian canc...
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian canc...
The objective of this study was to determine the prevalence of BRCA1 and BRCA2 gene mutations in uns...
Ovarian cancer is the most common cause of death from gynecological cancers in the Western world. Th...
Epithelial ovarian cancer (EOC) is a heterogeneous disease with a major heritable component. The dif...
BACKGROUND:Recent studies have identified several single nucleotide polymorphisms (SNPs) in the popu...
We report a novel BRCA1 germline 4156delAA mutation detected in a 41-year-old woman with breast and ...