Regulation of fatty acids metabolism in obesity

Pretilost je bolest modernog doba i predstavlja globalnu prijetnju svjetskom zdravstvu. Pretilost je stanje koje nastaje zbog povećanog nakupljanja masnog tkiva. Masno tkivo je glavno skladište triacilglicerola te ima veliku sposobnost plastičnosti. Masno tkivo je endokrini organ koji luči različite adipokine. Metabolizam masti osjetljiv je na promjene u prehrani te na različite hormone i adipokine koji specifično inhibiraju ili potiču sintezu ili razgradnju masnih kiselina. Masti se mogu povećano skladištiti i u drugim organima te izazivati brojne poremećaje i bolesti.Obesity is a disease of the modern age and represents a global threat to the world`s health. It is a condition caused by increased accumulation of fatty tissue. Fat tissue is the main store of triacylglycerol and has a great ability of plasticity. Fat tissue is an endocrine organ that secretes various adipokines. Fat metabolism is susceptible to dietary changes and various hormones as well as adipocines that specifically inhibit or induce the synthesis or oxidation of fatty acids. If the storage of fat in other organs is excessive it could cause many disorders and illnesses