SADS is defined as sudden death under the age of 40 years old in the absence of structural heart disease. Family screening studies are able to identify a cause in up to 50% of cases-most commonly long QT syndrome, Brugada and early repolarisation syndrome, and catecholaminergic polymorphic ventricular tachycardia using standard clinical screening investigations including pharmacological challenge testing. These diagnoses may be supported by genetic testing which can aid cascade screening and may help guide management. In the current era it is possible to undertake molecular autopsy provided suitable samples of DNA can be obtained from the proband. With the evolution of rapid sequencing techniques it is possible to sequence the whole exome f...
A genetic risk of sudden cardiac arrest and sudden death due to an arrhythmic cause, known as sudden...
Mutations involving cardiac ion channels result in abnormal action potential formation or propagatio...
Aims: Sudden arrhythmic death syndrome (SADS) is most often caused by heritable cardiac diseases. St...
Sudden arrhythmic death syndrome (SADS) describes a sudden death with negative autopsy and toxicolog...
Autopsy of sudden cardiac death (SCD) in the young shows a structurally and histologically normal he...
Sudden cardiac death in people between the ages of 1–40 years is a devastating event and is frequent...
Inherited arrhythmia (IA) is one of the main causes of sudden cardiac death (SCD) in young people, a...
AbstractSudden cardiac death (SCD) is a rare but devastating complication of a number of underlying ...
doi: 10.3389/fphys.2013.00199 The investigation of sudden arrhythmic death syndrome (SADS)—the curre...
There have been remarkable advances in our knowledge of the underlying heritability of cardiac arrhy...
Sudden cardiac death (SCD) in people before the age of 35 years is a devastating event for any famil...
Inherited arrhythmia syndromes, or “ion channelopathies”, is a term encompassing a number of differe...
Most sudden deaths are because of a cardiac etiology and are termed sudden cardiac death (SCD). In y...
BACKGROUND-: Sudden cardiac death is often caused by inherited arrhythmia syndromes, particularly if...
A genetic risk of sudden cardiac arrest and sudden death due to an arrhythmic cause, known as sudden...
A genetic risk of sudden cardiac arrest and sudden death due to an arrhythmic cause, known as sudden...
Mutations involving cardiac ion channels result in abnormal action potential formation or propagatio...
Aims: Sudden arrhythmic death syndrome (SADS) is most often caused by heritable cardiac diseases. St...
Sudden arrhythmic death syndrome (SADS) describes a sudden death with negative autopsy and toxicolog...
Autopsy of sudden cardiac death (SCD) in the young shows a structurally and histologically normal he...
Sudden cardiac death in people between the ages of 1–40 years is a devastating event and is frequent...
Inherited arrhythmia (IA) is one of the main causes of sudden cardiac death (SCD) in young people, a...
AbstractSudden cardiac death (SCD) is a rare but devastating complication of a number of underlying ...
doi: 10.3389/fphys.2013.00199 The investigation of sudden arrhythmic death syndrome (SADS)—the curre...
There have been remarkable advances in our knowledge of the underlying heritability of cardiac arrhy...
Sudden cardiac death (SCD) in people before the age of 35 years is a devastating event for any famil...
Inherited arrhythmia syndromes, or “ion channelopathies”, is a term encompassing a number of differe...
Most sudden deaths are because of a cardiac etiology and are termed sudden cardiac death (SCD). In y...
BACKGROUND-: Sudden cardiac death is often caused by inherited arrhythmia syndromes, particularly if...
A genetic risk of sudden cardiac arrest and sudden death due to an arrhythmic cause, known as sudden...
A genetic risk of sudden cardiac arrest and sudden death due to an arrhythmic cause, known as sudden...
Mutations involving cardiac ion channels result in abnormal action potential formation or propagatio...
Aims: Sudden arrhythmic death syndrome (SADS) is most often caused by heritable cardiac diseases. St...