The CCCTC-binding factor (CTCF) is a central regulator of chromatin topology recently linked to neurodevelopmental disorders such as intellectual disability, autism, and schizophrenia. The aim of this study was to identify novel roles of CTCF in the developing mouse brain. We provide evidence that CTCF is required for the expression of the LIM homeodomain factor LHX6 involved in fate determination of cortical interneurons (CINs) that originate in the medial ganglionic eminence (MGE). Conditiona
Summary: Mafb and c-Maf transcription factor (TF) expression is enriched in medial ganglionic eminen...
Formation of the cerebral cortex and commissures involves a complex developmental process defined by...
PURPOSE: Pathogenic variants in the chromatin organizer CTCF were previously reported in seven indiv...
The CCCTC-binding factor (CTCF) is a central regulator of chromatin topology recently linked to neur...
An increasing number of proteins involved in genome organization have been implicated in neurodevelo...
SummaryThe CCCTC-binding factor (CTCF) is a key molecule for chromatin conformational changes that p...
An imbalance of excitation and inhibition in key neural circuits is hypothesized to underlie some ep...
Emerging evidence implicates the regulation of higher-order chromatin structure in brain development...
Cortical interneurons originating in the embryonic medial ganglionic eminence (MGE) diverge into a r...
SummaryCortical GABAergic interneurons have essential roles for information processing and their dys...
SummaryCCCTC-binding factor (CTCF) is an organizer of higher-order chromatin structure and regulates...
Increasing evidence implicates chromatin structure and epigenetic regulation in various human develo...
CCCTC-binding factor (CTCF) is a conserved transcription factor with thousands of binding sites in m...
GABAergic interneurons of the cerebral cortex represent one of the most diversified populations of c...
Purpose: Pathogenic variants in the chromatin organizer CTCF were previously reported in seven indiv...
Summary: Mafb and c-Maf transcription factor (TF) expression is enriched in medial ganglionic eminen...
Formation of the cerebral cortex and commissures involves a complex developmental process defined by...
PURPOSE: Pathogenic variants in the chromatin organizer CTCF were previously reported in seven indiv...
The CCCTC-binding factor (CTCF) is a central regulator of chromatin topology recently linked to neur...
An increasing number of proteins involved in genome organization have been implicated in neurodevelo...
SummaryThe CCCTC-binding factor (CTCF) is a key molecule for chromatin conformational changes that p...
An imbalance of excitation and inhibition in key neural circuits is hypothesized to underlie some ep...
Emerging evidence implicates the regulation of higher-order chromatin structure in brain development...
Cortical interneurons originating in the embryonic medial ganglionic eminence (MGE) diverge into a r...
SummaryCortical GABAergic interneurons have essential roles for information processing and their dys...
SummaryCCCTC-binding factor (CTCF) is an organizer of higher-order chromatin structure and regulates...
Increasing evidence implicates chromatin structure and epigenetic regulation in various human develo...
CCCTC-binding factor (CTCF) is a conserved transcription factor with thousands of binding sites in m...
GABAergic interneurons of the cerebral cortex represent one of the most diversified populations of c...
Purpose: Pathogenic variants in the chromatin organizer CTCF were previously reported in seven indiv...
Summary: Mafb and c-Maf transcription factor (TF) expression is enriched in medial ganglionic eminen...
Formation of the cerebral cortex and commissures involves a complex developmental process defined by...
PURPOSE: Pathogenic variants in the chromatin organizer CTCF were previously reported in seven indiv...