GLOBULAR RESISTANCE MODIFICATION ON RATS CONSECUTIVELY TO Al2(SO4)3 ADDITION FOR TWO GENERATION

Some of the major modifications on membranes produced by the oxygen reactivespecies are membranal structure and functions modifications, lipids peroxydation,membranal protein alterations and transportation disturbances thru membranes.A series of xenobotics like oxidant pollutants, lead, aluminium and others directlyor indirectly are producing thru metabolization free radicals which interact withcells components and alterate their functions. The purpose of this paper was torelieve the impact of aluminium cumulative addition onto globular resistance onrats. Has been administrated three levels of aluminium (200ppb, 400 ppb şi 1000ppb) as Al2(SO4)3 ad libidum in water. Was followed their toxicity impact on theglobular resistance for two generations. The results indicate a decrease ofglobular resistance directly correlated with the aluminium addition