Many applications of modern science involve a large number of parameters. In many cases, the number of parameters, p, exceeds the number of observations, N. Classical multivariate statistics are based on the assumption that the number of parameters is fixed and the number of observations is large. Many of the classical techniques perform poorly, or are degenerate, in high-dimensional situations. In this work, we discuss and develop statistical methods for inference of data in which the number of parameters exceeds the number of observations. Specifically we look at the problems of hypothesis testing regarding and the estimation of the covariance matrix. A new test statistic is d...