A squamous cell carcinoma arising from scrotal epidermal cyst. A case report and review of 94 cases from the world literature

Epidermal cysts are a common benign skin abnormality, comprising 85–90% of all excised skin cysts. The term epidermal inclusion cyst refers specifically when the cyst resulted from the implantation of epidermal elements in the dermis. Squamous cell carcinomas (SCCs) are common skin lesions; however, a malignant transformation of an epidermal cyst is very rare with incidence of 0.011–0.045%. Few cases of malignant transformation of an epidermal cyst have been reported in the literature so far. This paper presents a case of squamous cell carcinoma arising from a scrotal epidermal cyst