PERBEDAAN DOSIS ALUMINIUM SULFAT (TAWAS) TERHADAP KUALITAS SPERMATOZOA DAN KADAR ALUMINIUM DALAM TESTIS MENCIT (Mus Musculus) SWISS WEBSTER

This study designated to evaluate the quality of reproductive organs system in the form of testicular weight, testicular volume and weight of epididymis; quality of spermatozoa include concentration, viability, motility, and morphology of spermatozoa; and aluminum accumulation in mice testis after administration of different aluminum sulfate dose, i.e., 0, 122,5, 245 and 490 mg/kg bb for 45 days were orally administrated using feeding tube through oral route for 45 days. The next objective is to evaluate the correlation between the doses of aluminum sulfate with each variable, as well as to assess the most influential doses of aluminum sulfate in reducing testicular weight and volume, epididymal weight, concentration, viability, motility, and morphology of cauda epididymal spermatozoa and increasing aluminum levels in testes Mice. The results showed that aluminum sulfate did not significantly (p>0.05) decrease testicular weight, testicular volume, epididymal weight, concentration and viability of spermatozoa, but significantly (p