Lake-level records from Italy suggest that patterns of precipitation in the central Mediterranean during the Holocene were divided between the north and south, but a scarcity of reliable palaeoclimatic records in the north and central-southern Mediterranean means new evidence is needed to validate this hypothesis. We provide robust quantitative estimates of Holocene climate in the Mediterranean region using four high-resolution pollen records from northern (Lakes Ledro and Accesa) and southern (Lakes Trifoglietti and Pergusa) Italy. Multiple methods are used to provide an improved assessment of the palaeoclimatic reconstruction uncertainty. The multi-method approach uses the pollen-based weighted averaging, weighted-average partial least-sq...