Body axis elongation represents a common and fundamental morphogenetic process in development. A key mechanism triggering body axis elongation without additional growth is convergent extension (CE), whereby a tissue undergoes simultaneous narrowing and extension. Both collective cell migration and cell intercalation are thought to drive CE and are used to different degrees in various species as they elongate their body axis. Here, we provide an overview of CE as a general strategy for body axis elongation and discuss conserved and divergent mechanisms underlying CE among different species
International audiencePosterior body elongation is a widespread mechanism propelling the generation ...
In vertebrate embryos, a process called somitogenesis lays the foundations of the adult spine. This ...
© 2020 The Authors.Intercalation allows cells to exchange positions in a spatially oriented manner i...
During development, vertebrate embryos undergo dramatic changes in shape. The lengthening and narrow...
In Xenopus and zebrafish, elongation of the anterior-posterior axis from a spherical early embryo de...
Convergent extension, the simultaneous extension and narrowing of tissues, is a crucial event in the...
AbstractConvergent extension, the simultaneous narrowing and lengthening of a tissue, plays a major ...
During early embryonic development, cell and tissue movements must be carefully orchestrated to prev...
BACKGROUND: The vertebrate body axis extends sequentially from the posterior tip of the embryo, fuel...
Tissue elongation is a necessary process in metazoans to implement their body plans that is not full...
How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, but less s...
AbstractThe antero-posterior dispersion of clonally related cells is a prominent feature of axis elo...
How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, but less s...
<div><p>How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, bu...
Germband extension (GBE) in the early Drosophila embryo provides a simple system in which to study c...
International audiencePosterior body elongation is a widespread mechanism propelling the generation ...
In vertebrate embryos, a process called somitogenesis lays the foundations of the adult spine. This ...
© 2020 The Authors.Intercalation allows cells to exchange positions in a spatially oriented manner i...
During development, vertebrate embryos undergo dramatic changes in shape. The lengthening and narrow...
In Xenopus and zebrafish, elongation of the anterior-posterior axis from a spherical early embryo de...
Convergent extension, the simultaneous extension and narrowing of tissues, is a crucial event in the...
AbstractConvergent extension, the simultaneous narrowing and lengthening of a tissue, plays a major ...
During early embryonic development, cell and tissue movements must be carefully orchestrated to prev...
BACKGROUND: The vertebrate body axis extends sequentially from the posterior tip of the embryo, fuel...
Tissue elongation is a necessary process in metazoans to implement their body plans that is not full...
How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, but less s...
AbstractThe antero-posterior dispersion of clonally related cells is a prominent feature of axis elo...
How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, but less s...
<div><p>How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, bu...
Germband extension (GBE) in the early Drosophila embryo provides a simple system in which to study c...
International audiencePosterior body elongation is a widespread mechanism propelling the generation ...
In vertebrate embryos, a process called somitogenesis lays the foundations of the adult spine. This ...
© 2020 The Authors.Intercalation allows cells to exchange positions in a spatially oriented manner i...