Recent perspectives on the pathogenesis of hepatitis E

Hepatitis E (HE)is an inflammatory liver disease caused by infection with the hepatitis E virus (HEV), and this virus was first documented as infectious agent in 1980s. And then, there were more and more studies on hepatitis E. This article presents a summary about hepatitis E from HEV genome, genotype（There are four genotypes of HEV, but only one serotype. Genotypes 1 and 2 exclusively infect humans, whereas genotypes 3 and 4 can also infect other animals, particularly pigs）, epidemiological investigation, detections and vaccines, treatment. And gives a prospect to the future research on the hepatitis E. Till now, hepatitis E vaccine will be a powerful weapon for the prevention of hepatitis E