Breast cancer with Human Epidermal Growth Factor Receptor (HER)2 overexpression increases tumor progession and lead to metastasis, which is primarily cause of mortality in breast cancer. Pentagamaboronon-0 Sorbitol (PGB-0-So) is an aquoeous formulation of curcumin analog, PGB-0, with sorbitol. This compound has been developed as an anti-cancer chemotherapeutic agent and a boron carrying pharmaceutical for boron neutron capture therapy (BNCT). The aims of this study are to investigate antimetastatic activities of PGB-0-So against HER2-overexpressed MCF-7 breast cancer (MCF-7/HER2) cells. The MTT cytotoxicity assay of PGB-0-So exhibited cytotoxic effect with an IC50 value of 35 μM. The testing of anti-migration activity using the scratch woun...
Curcumin has attracted great attention in the therapeutic arsenal in clinical oncology due to its ch...
The use of 5-fluorouracil (5-FU) in colon cancer as the primary chemotherapy has not been meet satis...
BACKGROUND: The anti-cancer properties of pentagamavunon-1 (PGV-1) and curcumin have been documented...
Mortality in cancer is primarily due to failure of metastasis prevention. One strategy to target the...
The incidence of Breast Cancer Metastasis (MBC) can be categorized in stage IV as well as being the ...
Development of chemotherapeutic agent and boron carrying pharmaceutical based on triple negative bre...
Development of chemotherapeutic agent and boron carrying pharmaceutical based on HER2 specific targe...
Breast cancer is the most common type of cancer causing mortality for women due to metastasis. More ...
HER2‐positive breast cancer is an aggressive form of the disease that is associated with poor progno...
Earlier findings reported the anticancer-mediated activities of curcumin-modified compounds Pentagam...
Senescence defined as an irreversible cell cycle arrest. Senescence can inhibit cancer growth and su...
The development of breast cancer at an advanced stage is signed with metastatic phenomenon, triggeri...
An improved compound of pentagamavunone-1 (PGV-1), chemoprevention-curcumin analog 1.1 (CCA-1.1), ha...
Pentagamavunone‐0 (PGV‐0) or 2,5‐bis(4’‐hydroxy‐3‐methoxybenzylidine)‐cyclopentanone is a curcumin a...
Breast cancer is the most prevalent form of cancer diagnosed in women, and there continues to be lim...
Curcumin has attracted great attention in the therapeutic arsenal in clinical oncology due to its ch...
The use of 5-fluorouracil (5-FU) in colon cancer as the primary chemotherapy has not been meet satis...
BACKGROUND: The anti-cancer properties of pentagamavunon-1 (PGV-1) and curcumin have been documented...
Mortality in cancer is primarily due to failure of metastasis prevention. One strategy to target the...
The incidence of Breast Cancer Metastasis (MBC) can be categorized in stage IV as well as being the ...
Development of chemotherapeutic agent and boron carrying pharmaceutical based on triple negative bre...
Development of chemotherapeutic agent and boron carrying pharmaceutical based on HER2 specific targe...
Breast cancer is the most common type of cancer causing mortality for women due to metastasis. More ...
HER2‐positive breast cancer is an aggressive form of the disease that is associated with poor progno...
Earlier findings reported the anticancer-mediated activities of curcumin-modified compounds Pentagam...
Senescence defined as an irreversible cell cycle arrest. Senescence can inhibit cancer growth and su...
The development of breast cancer at an advanced stage is signed with metastatic phenomenon, triggeri...
An improved compound of pentagamavunone-1 (PGV-1), chemoprevention-curcumin analog 1.1 (CCA-1.1), ha...
Pentagamavunone‐0 (PGV‐0) or 2,5‐bis(4’‐hydroxy‐3‐methoxybenzylidine)‐cyclopentanone is a curcumin a...
Breast cancer is the most prevalent form of cancer diagnosed in women, and there continues to be lim...
Curcumin has attracted great attention in the therapeutic arsenal in clinical oncology due to its ch...
The use of 5-fluorouracil (5-FU) in colon cancer as the primary chemotherapy has not been meet satis...
BACKGROUND: The anti-cancer properties of pentagamavunon-1 (PGV-1) and curcumin have been documented...