Side Effects of Metoclopramide (Reglan) Oral Overdose in Pediatric Patients

In pediatric ages are used for the treatment of frequent vomiting, especially at the age of 3 years old, medicines such as metoclopramide against vomiting from gastrointestinal disorders, ect. The most common use is Reglan solution, but its dose should be strictly observed because the therapeutic dose is limited, overdose is easily achievable to give expressive effects to the extrapyramidal central nervous system. Purpose of the study was to detect the frequent side-effects of the extrapyramidal nervous system that are due to the oral overdose of Reglan to the pediatric ages. Our study was done in the years 2014-2016 where all cases hospitalized by intoxication or oral overdose of Reglan solution in the outpatient service. These cases have been treated in the Pediatric Service in Elbasan. After having been diagnosed with signs of the nervous system from the overdose of Reglan solution they were surveyed in terms of dose taken, duration of use, age, ect. The17 cases diagnosed in our service have a seriously occurring clinic with cervical freezing and contractile bodywork associated with sleepiness. Out of these nine children were under 1 year old, 5 children 1-4 years old, and 3 children were aged 4-8 years. From these children under 1 year received Reglan solution at high doses 3 times 1 coffee spoon (also fivefold-tenfold of the dose) while the therapeutic dose for Reglan solution is 0.1mgr / kg in 3-4 doses. Side effects of Reglan overdose (Metocloperamide) are common in pediatric ages stemming from non-observance of the correct dosage while the distance between the normal dosage and the damaging dosage is approximate. This is the duty of the family doctor but especially of the pharmacists who have been greatly increased and not in the right qualification that the children especially under one year take Regal with drops rather than coffee spoon (2.5ml)