ストレス蛋白 (HSP 70) が運動による筋損傷・筋疲労の修復に及ぼす影響

Current interest is attracted to the problem on the correlation between physical exercise and heat shock induced protein (HSP 70), especially on the enhanced postischemic myocardial recovery following exercise induction of HSP 70. From the recent papers, the inducible isoform of the 70kDa heat shock protein (HSP) family, HSP 70kDa has been confirmed to protect cells from protein-damaging stressors and has been associated with not only myocardial protection but also recovery of several tissue damages. In the present review article, therefore, the related papers to exercise induced body hyperthermia, muscular damage and HSP 70 family, and their protection and/or recovery mechanism were collected and analyzed from the view-points of biological functions of stress protein HSP 70 family as well as of Granyl-Granyl Acetone (GGA) the HSP inducer