Damages of Ultrastructure in Rat Skeletal Muscles after Chysical Exercise

長期間のかなり激しい身体トレーニングが骨格筋組織にどのような変化を与えたかを調べることが本実験の目的である。1988年著者がソウルで行われたオリンピック科学会議に報告したものの一貫として, 今回もラットを用い, 9週間の水泳の後に幾つかの骨格筋組織を採集し, 電子顕微鏡で対照群との組織像の比較を行ったもので, 以下の如き結果が得られた。気泡を洗い落としたラットに水泳トレーニングを実施した翌日に, 遅筋成分の多い Soleus (ヒラメ筋) に組織の変性が見られ, Z-Line (Z-Band) の離脱やStreaming, さらに明白な組織像の変化が見られたが, EDL (長指伸筋) には同様変化が見られなかった。対照群と比べて Plantaris (足底筋) がとくに, ミトコンドリアの発達が見られた。ミトコンドリアは Subsarcolemma 及び Intermyofibrillar の両方とも発達が見られ, 数および大きさそして内膜突起の密度の増加も見られた。The purpose of this experiment is to investigate the possible effect of long term physical exercise which may cause some extend of damage in the skeletal muscles. Newly wened male Wister rats were used. The training by swimming was conducted for 9 weeks with 6 days a week in a special deviced pool. Tissues of skeletal muscle were cheaked by using electron microscope. The following results were noted : long-period of swimming exercise training caused a conspicuous damage in the skeletal muscles. The soleus is one of the tissue that is susceptable to the damage that induced by swimming exercise. The plantalis not in the EDL, suffered a similar damage to a lesser extent. This kind of damage in the exercised rats were not appeared in the control rats. Damage were streaming of Z-band and disruption of sarcomere. Number and size of mitochondria both in subsarcolemmal and intermyfibrillar space were increased following the training, particularly the plantaris muscle