Gaurav Sharma1, Kaushal Rege2,3, David E Budil4, Martin L Yarmush2,5, Constantinos Mavroidis11Department of Mechanical and Industrial Engineering; 4Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA; 2The Center for Engineering in Medicine (CEM), Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; 3Department of Chemical Engineering, Arizona State University, Tempe, AZ, USA; 5Department of Biomedical Engineering, Rutgers University, NJ, USAAbstract: We describe the molecular dynamics (MD)-aided engineering design of mutant peptides based on the α-helical coiled-coil GCN4 leucine zipper peptide (GCN4-p1) in order to obtain environmentally-responsive nanotweezers. The actua...
Toehold-mediated DNA strand displacement (TMSD) is a powerful tool for controlling DNA-based molecul...
The goal of this work was to study the highly specific nature of protein-DNA recognition, using a "...
The development of a switching system for guanine nanowire (G-wire) formation by external signals is...
The design hypothesis, architectures, and preliminary computational results of a peptide based nanoT...
The design hypothesis, architectures, and computational modeling of a novel peptide-based nanoactuat...
Artificial DNA looping peptides were engineered to study the roles of protein and DNA flexibility in...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2014."February 2014." ...
The rational design of peptides that fold to form discrete nanoscale objects, and/or self-assemble i...
We propose an experimental and simulative approach to study the effect of integrating a DNA function...
A novel multi-functional, proton-fueled DNA tweezers has been constructed. Starting from simple conf...
Inspired by the remarkable ability of natural protein switches to sense and respond to a wide range ...
Protein design studies using coiled coils have illustrated the potential of engineering simple pepti...
The ability to direct the assembly of inorganic nanoparticles using biomolecular recognition is of g...
Kükenshöner T, Wohlwend D, Niemoeller C, et al. Improving coiled coil stability while maintaining sp...
Thesis: Ph. D. in Medical Engineering and Medical Physics, Harvard-MIT Program in Health Sciences an...
Toehold-mediated DNA strand displacement (TMSD) is a powerful tool for controlling DNA-based molecul...
The goal of this work was to study the highly specific nature of protein-DNA recognition, using a "...
The development of a switching system for guanine nanowire (G-wire) formation by external signals is...
The design hypothesis, architectures, and preliminary computational results of a peptide based nanoT...
The design hypothesis, architectures, and computational modeling of a novel peptide-based nanoactuat...
Artificial DNA looping peptides were engineered to study the roles of protein and DNA flexibility in...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2014."February 2014." ...
The rational design of peptides that fold to form discrete nanoscale objects, and/or self-assemble i...
We propose an experimental and simulative approach to study the effect of integrating a DNA function...
A novel multi-functional, proton-fueled DNA tweezers has been constructed. Starting from simple conf...
Inspired by the remarkable ability of natural protein switches to sense and respond to a wide range ...
Protein design studies using coiled coils have illustrated the potential of engineering simple pepti...
The ability to direct the assembly of inorganic nanoparticles using biomolecular recognition is of g...
Kükenshöner T, Wohlwend D, Niemoeller C, et al. Improving coiled coil stability while maintaining sp...
Thesis: Ph. D. in Medical Engineering and Medical Physics, Harvard-MIT Program in Health Sciences an...
Toehold-mediated DNA strand displacement (TMSD) is a powerful tool for controlling DNA-based molecul...
The goal of this work was to study the highly specific nature of protein-DNA recognition, using a "...
The development of a switching system for guanine nanowire (G-wire) formation by external signals is...