In this mini-review we describe the different strategies for rational protein engineering and summarize the computational tools available. Computational tools can either be used to design focused libraries, to predict sequence-function relationships or for structure-based molecular modelling. This also includes de novo design of enzymes. Examples for protein engineering of aldolases and transaldolases are given in the second part of the mini-review
The main objective of this dissertation was to investigate the structure-function relationship in di...
Thesis (Ph.D.)--University of Washington, 2012Computational protein design is a relatively new techn...
Aldolases are seen as an attractive route to the production of biologically important compounds due ...
In this mini-review we describe the different strategies for rational protein engineering and summar...
AbstractIn this mini-review we describe the different strategies for rational protein engineering an...
Aldolases are seen as an attractive route to the production of biologically important compounds due ...
The creation of enzymes capable of catalyzing any desired chemical reaction is a grand challenge for...
The creation of enzymes capable of catalyzing any desired chemical reaction is a grand challenge for...
The creation of enzymes capable of catalyzing any desired chemical reaction is a grand challenge for...
Enzymes play a crucial role in modern biotechnology, industry, food processing and medical applicati...
A collection of computer tools designed for amino acid sequence analysis, model building and molecul...
A collection of computer tools designed for amino acid sequence analysis, model building and molecul...
Enzymes are powerful biocatalysts, however, so far there is still a large gap between the number of ...
Abstract: Enzymes are large biological molecules responsible for the thousands of metabolic processe...
Enzymes are tremendously proficient catalysts, which can be used as extracellular catalysts for a wh...
The main objective of this dissertation was to investigate the structure-function relationship in di...
Thesis (Ph.D.)--University of Washington, 2012Computational protein design is a relatively new techn...
Aldolases are seen as an attractive route to the production of biologically important compounds due ...
In this mini-review we describe the different strategies for rational protein engineering and summar...
AbstractIn this mini-review we describe the different strategies for rational protein engineering an...
Aldolases are seen as an attractive route to the production of biologically important compounds due ...
The creation of enzymes capable of catalyzing any desired chemical reaction is a grand challenge for...
The creation of enzymes capable of catalyzing any desired chemical reaction is a grand challenge for...
The creation of enzymes capable of catalyzing any desired chemical reaction is a grand challenge for...
Enzymes play a crucial role in modern biotechnology, industry, food processing and medical applicati...
A collection of computer tools designed for amino acid sequence analysis, model building and molecul...
A collection of computer tools designed for amino acid sequence analysis, model building and molecul...
Enzymes are powerful biocatalysts, however, so far there is still a large gap between the number of ...
Abstract: Enzymes are large biological molecules responsible for the thousands of metabolic processe...
Enzymes are tremendously proficient catalysts, which can be used as extracellular catalysts for a wh...
The main objective of this dissertation was to investigate the structure-function relationship in di...
Thesis (Ph.D.)--University of Washington, 2012Computational protein design is a relatively new techn...
Aldolases are seen as an attractive route to the production of biologically important compounds due ...