Publication date
July 2008
DOI Publisher
Springer Science and Business Media LLC ISSN
1742-4690 Journal
Retrovirology Citation count (estimate)
18Abstract
Abstract Accumulation of high levels of unintegrated viral DNA is a common feature of retroviral infection. It was recently discovered that coinfection of cells with integrated and unintegrated HIV-1 can result in complementation, allowing viral replication in the absence of integration. This new mode of HIV-1 replication has numerous implications for the function of unintegrated viral DNA and its application as a therapeutic vector.</p
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